Why is it important to set an appropriate FiO2 in mechanical ventilation?

Setting an appropriate fractional inspired oxygen concentration (FiO2) in mechanical ventilation is critical for ensuring adequate oxygen delivery to the patient while also minimizing the risk of oxygen toxicity. Oxygen toxicity can occur when the concentration of oxygen is too high for an extended period, leading to potential lung damage and other systemic effects. By adjusting the FiO2 to the lowest level that still maintains adequate oxygen saturation and delivery, clinicians can provide effective respiratory support while protecting patients from the adverse effects of excessive oxygen exposure.

Understanding the patient's condition, their baseline oxygen requirements, and monitoring their response to therapy are key in managing FiO2 correctly. This approach allows for a more individualized treatment plan that supports optimal respiratory function without unnecessary complications.