What is the target SpO2 range during mechanical ventilation?

The target SpO2 range during mechanical ventilation is typically 90% to 95%. This range is considered optimal as it provides sufficient oxygenation to maintain tissue perfusion and avoid hypoxia. SpO2 levels within this range help ensure that the body's organs and tissues receive an adequate supply of oxygen, which is particularly important for patients who may already be compromised by respiratory conditions or other medical issues.

Maintaining an SpO2 above 90% reduces the risk of detrimental effects associated with lower oxygen saturation levels, such as increased work of breathing and potential organ dysfunction. While higher levels, such as those in the 95% to 100% range, may be ideal from an oxygenation perspective, they can sometimes lead to complications, particularly in patients with certain lung pathologies. Consequently, the target of 90% to 95% strikes a balance between effective oxygenation and minimizing potential risks associated with hyperoxia.