What is the respiratory rate range for high-frequency positive pressure ventilation (HFPPV)?

High-frequency positive pressure ventilation (HFPPV) is employed to provide mechanical ventilation at significantly elevated respiratory rates, typically between 60 to 100 respirations per minute. This technique is designed to deliver small tidal volumes at high frequencies, thereby promoting adequate gas exchange while minimizing the risk of ventilator-induced lung injury.

The elevated respiratory rates in HFPPV allow for a more dynamic interaction between ventilation and perfusion, optimizing the distribution of ventilation in the lungs. By maintaining a high frequency, HFPPV also helps to reduce the risk of overdistension of alveoli that could occur with larger tidal volumes associated with lower respiratory rates. Thus, the range of 60 to 100 bpm is essential for achieving the therapeutic goals of this ventilation strategy.